ACC.24: Late-Breaking Science Video Collection
Published: 06 April 2024
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5943 -
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Views:
5943 -
Likes:
7
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Up Next
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14m 7sPart 2 | Session 2 Late-Breaker Discussion: The AEGIS-II Trial
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29m 8sPart 2 | Session 3 Late-Breaker Discussion: The RELIEVE-HF Trial
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23m 6sPart 2 | Session 4 Late-Breaker Discussion: The ARISE-HF Trial
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5m 50s
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7m 49sPart 3 | Session 2 Zilbesiran in Patients With Hypertension: KARDIA-2
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3m 40s
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7m 18s
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6m 40sPart 3 | Session 5 Chelation Therapy in Post-MI Pts with Diabetes: TACT2
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6m 41sPart 3 | Session 6 Semaglutide in Patients with HfpEF, Obesity and Diabetes: STEP HFpEF
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5m 41sPart 3 | Session 7 Self-Expanding vs Balloon Expandable TAVR: The SMART Trial
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3m 37s
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4m 35sPart 3 | Session 9 Technology-Assisted Nonprescription Rosuvastatin: TACTiC
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4m 45sPart 3 | Session 10 Coronary Sinus Reducer in Refractory Angina: ORBITA COSMIC
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2m 30sPart 3 | Session 11 TAVI Vs SAVR in Patients with Severe Aortic Valve Stenosis: DEDICATE-DZHK6
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4m 17s
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6m 45sPart 4 | Session 1 Artificial Intelligence in Cardiology: What You Need to Know in 2024
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6m 21sPart 4 | Session 2 Weight Loss Medications: What You Need to Know in 2024
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43m 48sPart 1 | Session 1 ACC.24 Late-breaking Science Wrap Up Nicolas M Van Mieghem, Joost Daemen
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28m 9sPart 1 | Session 2 What's Hot at ACC.24? Late-breaking Science Preview Nicolas M Van Mieghem, Joost Daemen
Overview
Our recurring review series, View from the Thoraxcenter, hosted by Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcentre, Erasmus MC, Rotterdam, NL) offers a thorough examination of late-breaking and featured scientific findings, highlighting significant data.
To delve deeper into the pivotal clinical trial data unveiled at ACC 24, Dr Harriette Van Spall (McMaster University, Hamilton, CA) conducts interviews with the principal investigators as part of her Late-Breaker Discussion Series.
For brief and focused coverage of the essential data unveiled, our accessible Expert Interviews were conducted with a select group of faculty members, concentrating on the results, relevance, and implications for future research.
Watch our Behind the Heart series to learn more the personal perspectives from the investigators behind top trials in cardiovascular science.
More from this programme
Part 1
View from the Thoraxcenter
In these concise episodes of View from the Thoraxcenter, Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcentre, Erasmus MC, Rotterdam, NL) offer their thoughts on the top late-breaking trials that will be presented at ACC.24.
Part 2
Late-Breaker Discussion Series
Host, Dr Harriette Van Spall is joined by principal investigators for discussion on selected late-breaking trials.
Part 3
Expert Interviews
Expert Interviews conducted with a select group of faculty members, concentrating on the results, relevance, and implications for future research.
Part 4
Highlights
Part 5
Behind the Heart
Watch our Behind the Heart series to learn more the personal perspectives from the investigators behind top trials in cardiovascular science.
About the episode
ACC.24 — Join Late-Breaker host, Dr Harriette Van Spall (McMaster University, CA), and Principal Investigator, Dr Javed Butler (University of Mississippi Medical Center, US), as they discuss the key findings from the EMPACT-MI trial (Boehringer Ingelheim)(NCT04509674).
In this multicentre, randomised, parallel group, double-blind placebo-controlled superiority trial, investigators evaluated the effect of empagliflozin, an SGLT2 inhibitor, on hospitalisation for heart failure (HF) and mortality in patients with acute myocardial infarction (MI).
The trial recruited 6522 participants, including eligible patients who presented with spontaneous MI alongside new signs or symptoms of pulmonary congestion requiring treatment, new left ventricular dysfunction (LVEF < 45%), and at least one additional risk factor for the development of future HF. The primary outcome measure was the composite of time to first heart failure hospitalisation or all-cause mortality up to 26 months.
Findings, presented at ACC.24 showed that empagliflozin did not significantly reduce the risk of time to first HHF or all-cause death following AMI. Furthermore, empagliflozin demonstrated 23% and 33% relative risk reduction of first HHF and total HHF, components of the primary and first key secondary endpoints respectively.
Recorded remotely from Jackson and Hamilton, 2024.
Support: This is an independent content produced by Radcliffe Cardiology.
Editor: Mirjam Boros
Videographer: Mike Knight
Faculty Biographies
Harriette Van Spall
Associate Professor of Medicine, Director of E-Health and Virtual Care
Dr Harriette Van Spall is an Associate Professor of Medicine and cardiologist and serves as Director of E-Health at McMaster University, Canada. She completed her medical and postgraduate clinical training at the University of Toronto and earned a Master of Public Health degree at Harvard University, US. Dr Van Spall is a Canadian Institutes of Health Research-funded clinical trialist and researcher with a focus on heart failure, health services, and health disparities.
She has garnered more than $4 million in research funding, has won several research awards, and has published her work in high-impact medical journals. She is an invited speaker, media correspondent, and editorial board member active in peer review at several high-impact medications journals and grant funding agencies, including Canadian Institutes of Health Research and Heart and Stroke Foundation of Canada.
Dr Van Spall is an Editorial Board…
Javed Butler
Professor of Medicine
Dr Javed Butler is President, Baylor Scott and White Research Institute, Senior Vice President for the Baylor Scott and White Health and Professor of Medicine at the University of Mississippi, US. He is board certified in cardiovascular medicine and advanced heart failure and transplant medicine. His research interests focus on clinical trials in patients with heart failure.
He serves on several national committees for the American College of Cardiology, American Heart Association, National Institutes of Health, and the Heart Failure Society of America. He is the recipient of the Simon Dack Award by the American College of Cardiology as well as the Time, Feeling, and Focus Award by the American Heart Association.
Prof Butler has authored more than 900 peer-reviewed publications. He serves on the editorial board of several peer reviewed cardiovascular journals and has been cited numerous times in America’s Best Doctors list.
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