ACC 2023: Late-Breaking Science Video Collection

Published: 06 March 2023

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Overview

Our regular review series View from the Thoraxcenter, hosted by Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcentre, Erasmus MC, Rotterdam, NL) provides a critical analysis of the late-breaking and featured science results and spotlights impactful data. 

 

For a deeper look into the key clinical trial data revealed at ACC 23, Dr Harriette Van Spall (McMaster University, Hamilton, CA) interviews the principal investigators in her regular Late-Breaker Discussion Series. 

 

For short, concise coverage of the key data revealed, our accessible Expert Interviews were conducted with select faculty, focussing on the results, applicability and impact on future research. 

More from this programme

Part 1

Late-Breaker Discussion Series

Host, Dr Harriette Van Spall is joined by principle investigators for discussion on selected late-breaking trials.  

5 sessions
The CLEAR-Outcomes Trial with Dr Harriette Van Spall & Dr Steven Nissen Watch now
The REVIVED-BCIS2 Viability Study with Dr Harriette Van Spall, Dr Divaka Perera & Dr Peter O'Kane Watch now
The BETTER-CARE HF Trial with Dr Harriette Van Spall & Dr Amrita Mukhopadhyay Watch now
The COORDINATE-Diabetes Trial with Dr Harriette Van Spall, Dr Neha J Pagidipati & Dr Christopher B Granger Watch now
The BIOVASC Trial with Dr Harriette Van Spall & Prof Roberto Diletti Watch now

Part 2

Expert Interviews

11 sessions
Statins to Protect Heart During Cancer Treatment: The STOP-CA Trial Watch now
RENOVATE-COMPLEX-PCI: IVUS Vs OCT Optimisation in Complex PCI Watch now
Effect of Evolocumab on Coronary Plaque Morphology: The YELLOW III Study Watch now
Mini-Thoracotomy Vs Sternoctomy for Degenerative Valve Disease: The UK Mini-Mitral Study Watch now
TAVR in Low-Risk Aortic Stenosis Patients: 3-Year Results From the Evolut Low Risk Trial Watch now
Pulsed Field Ablation in Persistent Atrial Fibrillation Patients: The PULSED AF Trial Watch now
MK-0616: Oral PCSK9 inhibitor In Hypercholesterolemia Patients Watch now
Evaluation of the Mechanism of Benefit for Dapagliflozin in HFpEF Watch now
BMAD Trial: μCor in Ambulatory Decompensated Heart Failure Watch now
The STELLAR Phase II Trial: Sotatercept in Patients With Pulmonary Arterial Hypertension Watch now
Inflammatory Risk from Statin-Treated Patients: Findings from PROMINENT, REDUCE-IT and STRENGTH Watch now

Part 3

View from the Thoraxcenter

In these concise episodes of View from the Thoraxcenter, Prof Nicolas Van Mieghem and Dr Joost Daemen (Thoraxcentre, Erasmus MC, Rotterdam, NL) offer their thoughts on the top late-breaking trials that will be presented at ACC 2023. 

2 sessions
ACC.23 Late-breaking Science Wrap Up Watch now
What's Hot at ACC.23? Late-breaking Science Preview Watch now

Part 4

Highlights Reviews

4 sessions
Interventional Late-breaking Highlights with Dr Mirvat Alasnag & Dr Khaled Al-Shaibi Watch now
Lipid Management & the CLEAR Trial with Dr Erin Michos Watch now
Obesity Management Strategies in 2023 with Dr Harold Bays Watch now
ACC.23 President Interview with Dr B Hadley Wilson Watch now

Part 5

Behind the Heart

Watch our Behind the Heart series to learn more the personal perspectives from the investigators behind top trials in cardiovascular science.

7 sessions
Dr Akowuah: Cardiovascular Research & Message for Early-Career Researchers Watch now
Dr Kini: Asking Questions & Her Motivation to Do Research on Plaque Watch now
Drs Day, Lambert & Ackerman: Passion For Cardiovascular Research & Advice for Researchers Watch now
Dr Verma: Passion for Electrophysiology & His Advice For Young Researchers Watch now
Dr Wilson on Why Did He Choose Cardiology & His Advice for Early-career Faculty Watch now
Dr Hahn: Innovative Areas of Cardiovascular Science in 2023 Watch now
Dr Forrest: Structural Heart Innovations and Advice to Young Researchers Watch now

About the episode

Prof Nicolas Van Mieghem and Dr Joost Daemen return with their critical review series, View from the Thoraxcenter, to preview the most anticipated late-breaking and featured science trials of ACC.23.

Which trials have the potential to change practice? What are the key considerations for patient care and research? What is the context of the top trials of ACC?

Trials covered in detail include:


9:22: REVIVED-BCIS2: Effect of Myocardial Viability, Percutaneous Coronary Intervention and Functional Recovery on Clinical Outcomes
11:28: RENOVATE-COMPLEX-PCI: Intravascular Imaging-guided Versus Angiography-guided Procedural Optimization in Complex Percutaneous Coronary Intervention
14:19: BIOVASC: Complete Revascularization Strategies in Patients Presenting with Acute Coronary Syndromes and Multivessel Coronary Disease
15:55: Yellow III: Effect Of Evolocumab On Coronary Plaque Characteristics in Stable Coronary Artery Disease: A Multimodality Imaging Study 
18:03: CLEAR Outcomes: Bempedoic Acid and Cardiovascular Outcomes in Statin Intolerant Patients At High Cardiovascular Risk
20:41: MK-0616: Efficacy And Safety of The Oral PCSK9 Inhibitor, MK-0616, A Macrocyclic Peptide, in the Treatment Of Hypercholesterolemia: A Phase 2b Randomized Placebo-Controlled Clinical Trial

Don't miss out on the latest developments in cardiology research!

Faculty Biographies

Nicolas M Van Mieghem

Nicolas M Van Mieghem

Medical Director

Prof Nicolas Maria Van Mieghem is an Interventional cardiologist at Thoraxcenter, Erasmus MC, Rotterdam, NL decided to pursue a career that would help others. “I enjoy the feeling of being able to help someone or do something important for them". His father was a general cardiologist and one of his biggest influences early in his career.

Prof Van Mieghem initially intended to train as a cardiac surgeon but decided to specialise in interventional cardiology instead, following advice from a mentor. This decision was cemented when he read the first-in-human case report of transcatheter aortic valve implantation (TAVI) in Circulation by Alain Cribier in 2002. Prof Van Mieghem believes that great cardiologist genuinely cares for their patients. He names Gary Roubin, Dr Manu Malbrain and Professor Patrick Serruys among his mentors. 

His current research focuses on cerebral embolic protection during TAVI and the search for improved…

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Joost Daemen

Joost Daemen

Interventional Cardiologist

Dr Joost Daemen is a senior interventional cardiologist at the Thorax Center, Erasmus MC, Rotterdam, NL. Dr Daemen obtained his degree in medicine at the Erasmus University Medical Center. He is actively involved in several drug-eluting stent trials and is Principal Investigator of four trials focusing on the safety and efficacy of renal sympathetic denervation in hypertension, heart failure, vasospastic angina and heart failure. Dr Daemen is a member of the editorial board of EuroIntervention and the Netherlands Heart Journal, member of Young ICIN, and has completed courses in biomedical statistics and device training.

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